HORDB

ID: hor004401
Uniprot ID: P22690
Protein name: Ranatachykinin C
Gene name: NA
Organism: Lithobates catesbeianus (American bullfrog) (Rana catesbeiana)
Family: Tachykinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Lithobates (genus), Ranidae (family), Ranoidea (superfamily), Neobatrachia (suborder), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004401_AF2.pdb

hor004401_ESM.pdb

Mass:	124699	Formula:	C49H75N13O13S
Absent amino acids:	CDEKQRTVWY	Common amino acids:	AFGHILMNPS
pI:	7.55	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	4
Hydrophobicity:	53	Boman Index:	322
Half-Life:	3.5 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	88
Instability Index:	4906	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 2043143
Title: Isolation of four novel tachykinins from frog (Rana catesbeiana) brain and intestine.
PubMed ID: 8210506
Title: Four novel tachykinins in frog (Rana catesbeiana) brain and intestine.